GWAS Catalog

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GWAS Catalog (EBI/NHGRI) — look up SNPs by rsID, retrieve trait/disease associations with effect sizes, and find genome-wide association studies by trait.

3 tools
0ms auth
free tier 50 calls/day

Tools

get_snp

GWAS Catalog: look up a single-nucleotide polymorphism (SNP) by rsID. Returns functional class, chromosome/region locations, and mapped genes (with up/downstream + distance). Keyless, from EBI/NHGRI.

No parameters required.

▶ Try it
snp_associations

GWAS Catalog: get trait/disease associations for a SNP (rsID) — risk allele, p-value, odds ratio per copy, beta/effect size, and risk allele frequency. Keyless, from EBI/NHGRI.

No parameters required.

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studies_by_trait

GWAS Catalog: find genome-wide association studies for a disease/trait (EFO trait, e.g. "asthma" or "type 2 diabetes"). Returns accession, PubMed ID, title, journal, date, sample size. Keyless, from E

No parameters required.

▶ Try it

Test with curl

The gateway speaks JSON-RPC 2.0 over HTTP POST. You can test any pack directly from the terminal.

List available tools
bash 
curl -X POST https://gateway.pipeworx.io/gwas-catalog/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/list"}'
Call a tool
bash 
curl -X POST https://gateway.pipeworx.io/gwas-catalog/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":2,"method":"tools/call","params":{"name":"get_snp","arguments":{}}}'

Use with the SDK

Install @pipeworx/sdk to call tools from any TypeScript/Node project.

TypeScript 
import { Pipeworx } from '@pipeworx/sdk';
const px = new Pipeworx();
const result = await px.call("get_snp", {});
ask_pipeworx 
// Or ask in plain English:
const answer = await px.ask("gwas catalog (ebi/nhgri) — look up snps by rsid, retrieve trait/disease associations with effect sizes, and find genome-wide association studies by trait");